HOTAIR: An Oncogenic Long Non-Coding RNA in Human Cancer
نویسندگان
چکیده
منابع مشابه
HOTAIR: an oncogenic long non-coding RNA in different cancers
Long non-coding RNAs (lncRNAs) refer to a group of RNAs that are usually more than 200 nucleotides and are not involved in protein generation. Instead, lncRNAs are involved in different regulatory processes, such as regulation of gene expression. Different lncRNAs exist throughout the genome. LncRNAs are also known for their roles in different human diseases such as cancer. HOTAIR is an lncRNA ...
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متن کاملLong non-coding RNA HOTAIR in carcinogenesis and metastasis.
Long non-coding RNAs (lncRNAs) have gained massive attention in recent years as a potentially new and crucial layer of gene regulation. LncRNAs are prevalently transcribed in the genome, but their roles in gene regulation and disease development are largely unknown. HOX antisense intergenic RNA (HOTAIR), a lncRNA located in the HOXC locus, has been shown to repress HOXD gene expression and prom...
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ژورنال
عنوان ژورنال: Cellular Physiology and Biochemistry
سال: 2018
ISSN: 1015-8987,1421-9778
DOI: 10.1159/000490131